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The aim of radiotherapy is to destroy the cancer if possible without damaging the surrounding normal tissues. Two modalities of external beam radiotherapy and brachytherapy can be combined or used individually. Four parameters form the basis of radiobiology: repair, reoxygenation, repopulation and redistribution. The doses of radiotherapy employed in treating carcinoma of the cervix depend particularly on the intracavitary technique and equipment used. The design of radiotherapy for carcinoma of the cervix depends on the extent of the cancer. The radiation tolerance of normal tissues is related to the acute or chronic radiation reactions that occur in them. Primary radiotherapy may be used for patients who are unfit for surgery. Radiotherapy was formerly used in the treatment of ovarian cancer. There is a survival advantage for chemoradiation over radiotherapy alone in cervical cancer. Radiotherapy is widely used in vulval cancer as adjuvant treatment.
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